Welcome to Wortzel Lab, Tel Aviv University
At the Wortzel Lab, we investigate how cancer cells communicate with their environment through extracellular vesicles (EVs), with a particular focus on DNA associated with EVs. Our research uncovers how EV-DNA shapes tumor–immune interactions, influences anti-tumor immunity, and affects metastatic progression. By combining advanced genomics, imaging, and in-vivo cancer models, we aim to decode the molecular mechanisms governing EV-DNA biology and leverage this knowledge to improve early detection and develop new therapeutic strategies against metastasis.
Our Research Focus
EVs carry a wide variety of biomolecules, including DNA. We study the biology and function of EV-associated DNA (EV-DNA) in cancer progression and metastatic defense: how chromatinized DNA is packaged into EVs, how recipient cells detect and respond to it, and how these signals reshape local tissues and systemic immunity
 ONI TrainingScience takes you places! Before our lab officially opened, our PI, Dr. Inbal Wortzel, traveled to the ONI headquarters in Oxford for advanced equipment training. Mastering these state-of-the-art techniques ensures our team has the best possible tools for our upcoming research. |  Thank you very much Zuckerman FundOur PI, Dr. Inbal Wortzel, alongside the Lina Deshilton from the Zuckerman Fund. We are deeply grateful to the Zuckerman STEM Leadership Program for their generous support, which helps make our cutting-edge research and this new lab space possible. |  Setteling in with the top research teamA huge thank you to our colleagues for their guidance and support as we officially launch our new lab space |  Wortzel Lab TeamA new chapter begins! We celebrated the official opening of our newly renovated lab with the whole team. After affixing the mezuzah, we took a moment to look forward to all the groundbreaking science and discovery that will take place here. |
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 Ultracentrifuges Are Here!Our two brand new BeckmanCulter Ultracentrifuges are here. prof. Duck Named them Ben and Jerry. We are ready to work Full Time! |  Unwrapped!We were so exited to receive our newly renovated lab at TAU. Come Meet us at the Gray Faculty of Medical and Health Sciences |  ISEV 2026Dr. Wortzel giving her talk at ISEV 2026 as usual wowing the crowds! the autograph line is already packed! |  Prof. Duck is a Green Thumb!Decorating our new office space! |
 Prof. DuckDoing Science Requires the correct company, Come and look at the work we do here at the Wortzel Lab in TAU. Prof. Duck will be there too |  Happy Birthday Inbal!Celebrating Dr. Wortzel's birthday in the lab. See? we have fun here |  Summing up Prof. Lyden's VisitSumming up two days of Prof. David Lyden, our scientific Godfather, visiting Israel and our lab. |  Interacellular Dialogue WIZDr. Wrotzel presenting her discoveries at the WIZ Intercellular Dialogue in the Tumor Microenviorment. What a day of interesting and innovative research talks |
 Woman and Girls In Science DayOur lab is Proud to be one of three labs chosen to appear in TAU's Woman and Girls In Science Day, You can read all about that in the article! |  Hands On PI!!Dr. Wortzel one-uping all the other PIs and doing some hands on teaching to her research students |  Thank you TAU.nano!Closing a great workshop involving many researchers from the Koum center for nanotechnology all handling nano-particles in some way. |  We Arrived!the 14th annual Nano-Center Workshop we are here, now you can start |
 The most popular speakerDr. Wortzel wowing the crowd with her talk on EV-DNA |  More Glisons!We are keeping our high standard. Aml receiving her new set of Gilson Pipettes |  View From Our labMake sure to look outside between assays! |  Welcome AmlWelcoming our newest team member Aml. We keep moving forward |
 Gilson PipettesOnly the best for our lab! Exited to receive our Gilson Pipettes |  Starting OffStarted receiving reagents and prepping for assays |  First Team LunchSo exited to kick off with a full team ready for research |  ZetaViewPartical Metrix's advanced NTA system is here and ready |
Upcoming Apperances
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